QUE: WHAT IS ALDOL CONDENSATION ?
ANS: Aldehydes which have alpha hydrogen condense to give beta hydroxy aldehyde is called aldol condensation.
mechanism : aldol condensation can be both base as well as acid catalzedbase catalyzed mech is given below.
step 1: base first remove alpha hydrogen result into generation of enolate .
step 2: enolate attacks at carbonyl carbon which is electrophillic centre .
Base catalyzed mechanism of aldol condensation |
Ketone can also give aldol condensation however yield is very poor as effect of two R group decrease the electrophillicity of carbonyl carbon.
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